Trulicity and Ozempic are each once-weekly GLP-1 agonist injections used to decrease blood sugar ranges in individuals with sort 2 diabetes.
This text will discover the important thing similarities and variations that can assist you decide which medicine is perhaps best for you.
What are Trulicity and Ozempic?
Trulicity and Ozempic are name-brand injectable medication categorized as GLP-1 agonists. Each are authorised by the U.S. Meals and Drug Administration (FDA) to handle blood sugar ranges in individuals with sort 2 diabetes.
Trulicity is authorised for kids ages 10 and up and adults, whereas Ozempic is authorised for adults solely.
Each drugs may also assist with weight reduction and assist forestall stroke, coronary heart assault, and untimely loss of life in these with sort 2 diabetes and preexisting coronary heart illness.
Learn extra in: All the pieces You Have to Know About Trulicity and All the pieces You Have to Know About Ozempic.
Why would you’re taking Trulicity or Ozempic?
Chances are you’ll be prescribed one in all these medicines in case you have sort 2 diabetes, significantly in case you are coping with insulin resistance, persistent excessive blood sugar (particularly after meals), and issue sustaining a wholesome weight.
Research point out that GLP-1 agonists like Ozempic and Trulicity can promote weight reduction, though neither is FDA-approved for this function.
If prescribed off-label (in a fashion not formally authorised by the FDA), these drugs might also be used to enhance insulin sensitivity and assist with weight reduction, even in these with out sort 2 diabetes. At all times take them beneath a health care provider’s steering.
See extra in: All the pieces You Have to Know About Trulicity and All the pieces You Have to Know About Ozempic.
How are Trulicity and Ozempic comparable?
Trulicity and Ozempic share a number of similarities:
They don’t substitute insulin
These drugs don’t substitute insulin however can complement it in managing blood sugar ranges over time.
They assist decrease blood sugar step by step with out inflicting acute hypoglycemia (low blood sugar).
As insulin resistance decreases, chances are you’ll require much less insulin to handle your blood sugar ranges.
They’re injectable drugs, taken as soon as every week
Each can be found solely as subcutaneous (beneath the pores and skin) injections, taken as soon as every week.
It’s vital to keep up consistency by administering the therapy on the identical day and on the similar time every week.
They’ve comparable negative effects
Trulicity and Ozempic share many negative effects, which can embrace:
- Nausea
- Vomiting
- Diarrhea
- Stomachache
- Suppressed urge for food
- Weight reduction
- Constipation
- Fatigue
- Low blood sugar (if used with insulin)
Each drugs, although not often, can improve the danger of growing medullary thyroid carcinoma (MTC). You probably have a private or household historical past of MTC, it is best to keep away from these drugs.
Moreover, the FDA has issued a black field warning for each medication relating to their affiliation with an elevated danger of thyroid most cancers.
Learn extra in: Trulicity Aspect Results: What You Have to Know and Ozempic Aspect Results: What You Have to Know.
They trigger weight reduction and decrease blood sugar ranges
Each Trulicity and Ozempic successfully decrease blood sugar ranges and promote weight reduction.
Though not FDA-approved particularly for weight reduction, many individuals expertise a discount of greater than 5 % of their physique weight whereas taking these drugs.
Since they aren’t authorised for weight reduction, there isn’t any advisable dosage particularly for that function.
If you happen to’re contemplating choices for managing your weight, Trulicity or Ozempic is perhaps appropriate decisions to debate along with your healthcare supplier.
Learn extra in: Trulicity and Weight Loss: Can Trulicity Assist You Lose Weight? and Can Ozempic Assist You Lose Weight?
They are often taken with or with out meals
The medicines could be taken with or with out meals, not like insulin, which might trigger sudden drops in blood sugar.
The perfect time to take your dose is while you’re almost definitely to recollect it every week.
See extra in: Trulicity Dosing: How A lot Ought to You Take? and Ozempic Dosage Information: How A lot Ought to You Take?
Whereas not required, having a small snack earlier than or after your injection could assist alleviate nausea.
Go for bland meals like bananas, rice, toast, applesauce, or clear-broth soups. Weight-reduction plan performs an important position when adjusting to a brand new medicine, so be conscious of the meals you select.
See extra in: Meals to Keep away from When Taking Trulicity and Meals to Keep away from Whereas Taking Ozempic.
How are Trulicity and Ozempic totally different?
Though comparable, the drugs have key variations.
Their lively elements are totally different
Though Trulicity and Ozempic are each GLP-1 agonists, they differ of their lively elements. Trulicity comprises dulaglutide, whereas Ozempic comprises semaglutide.
If you’re allergic to both of those elements, seek the advice of your physician earlier than beginning therapy, as you may expertise extreme negative effects.
Ozempic could also be more practical
In a pivotal research evaluating semaglutide (Ozempic) and dulaglutide (Trulicity) in individuals with sort 2 diabetes, semaglutide was discovered to be more practical at bettering blood sugar administration and decreasing physique weight at each excessive and low doses, with an analogous security profile.
If you happen to’re coping with extreme insulin resistance and issue sustaining a wholesome weight, take into account discussing Ozempic along with your physician to see if it is perhaps a great match for you.
Continuously requested questions
Can I change between the 2?
Sure, it’s attainable to change between Trulicity and Ozempic.
Nevertheless, your healthcare supplier will seemingly suggest ready every week after your final dose of 1 earlier than beginning the opposite to attenuate the danger of extreme negative effects.
If you happen to’re allergic to both of their lively elements — semaglutide in Ozempic or dulaglutide in Trulicity — you shouldn’t change between them.
If you happen to’re experiencing important negative effects with one, making an attempt the opposite is perhaps a greater choice, as your physique could tolerate it otherwise.
Can I take each on the similar time?
No, you can’t take Trulicity and Ozempic collectively, despite the fact that they’ve totally different lively elements.
Double-dosing GLP-1 agonists can result in extreme negative effects, together with dangerously low blood sugar, which might be life-threatening if not handled.
If you happen to by accident take each drugs on the similar time or inside a 2-day interval, name your physician instantly or search emergency medical consideration.
Which medicine is correct for me?
Selecting between Trulicity and Ozempic is a choice that you simply and your healthcare supplier ought to make collectively, based mostly in your well being historical past, targets, life-style, and preferences.
At all times take into account the lively elements and any potential allergic reactions. Moreover, test your medical health insurance protection to see which drugs are on the popular drug listing, making certain you choose an inexpensive, long-term choice.
Whereas there aren’t any generic variations of Trulicity or Ozempic, your physician could counsel extra inexpensive options.
Study extra in All the pieces You Have to Know About Trulicity and All the pieces You Have to Know About Ozempic. Did you discover this text useful? Click on Sure or No beneath to tell us!
